Voxel-based morphometry in autopsy proven PSP and CBD
نویسندگان
چکیده
منابع مشابه
Voxel-Based Morphometry
The human brain is in a state of constant change and adaptation. This may be driven either by normal developmental or aging processes or by the effects of learning, training, and new occurrences in daily life. In addition to these aforementioned changes, more systematic influences such as gender, disease, and genes affect the brain’s structure. Using magnetic resonance imaging, brain changes an...
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An underlying assumption of the above parametric approach is that the process is a = Gaussian field, i.e., its statistical characteristics, including its roughness parameter (or its reciprocal, the smoothness ) ), are the same at each point in the image. The FWHM of the process should be constant in all directions and across all voxels in the image. While these assumptions are reasonable for fu...
متن کاملStratified Voxel-Based Morphometry (sVBM)
In neuroimaging, voxel based morphometry (VBM) has been a valuable tool of identifying brain-wide differences between populations. One of the key elements of VBM is to define a space for voxelwise comparisons. However, errors in this mapping to common space and variations of brain morphology, both natural and pathologic can result in false positives. In this work we explore a new framework, whe...
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At its simplest, voxel-based morphometry (VBM) involves a voxel-wise comparison of the local concentration of gray matter between two groups of subjects. The procedure is relatively straightforward and involves spatially normalizing high-resolution images from all the subjects in the study into the same stereotactic space. This is followed by segmenting the gray matter from the spatially normal...
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We thank the editorial staff and Dr. Ghosh-Dastidar and colleagues for their commentary on our manuscript “Relationship of Cognitive Measures and Gray and White Matter In Alzheimer’s Disease” [1]. Dr. GhoshDastidar and colleagues have provided an overview of voxel-based morphometry methodology as well as the strengths and limitations of utilizing this technique in investigating MRI features don...
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ژورنال
عنوان ژورنال: Neurobiology of Aging
سال: 2008
ISSN: 0197-4580
DOI: 10.1016/j.neurobiolaging.2006.09.019